Personalized Brain Imaging May Enhance TMS Treatment for Depression

A new randomized clinical trial from Mass General Brigham suggests that tailoring transcranial magnetic stimulation (TMS) using personalized brain imaging could lead to better results for individuals with treatment-resistant depression. Published in JAMA Psychiatry, the study found that participants receiving connectivity-based targeting experienced significantly greater improvement in depressive symptoms. This approach offers a more precise and potentially effective method for managing severe depression.