Adjunctive Antimicrobial Photodynamic Therapy in Non-Surgical Periodontal Treatment: Clinical and Microbiological Insights

A randomized split-mouth trial, published in MDPI, investigated adjunctive antimicrobial photodynamic therapy (aPDT) in non-surgical periodontal treatment. The study found significant greater variations in probing pocket depth (PPD), bleeding on probing (BOP), and plaque index (PI) in the aPDT group at 90 days compared to the control group, which only showed a significant reduction in PI. No statistically significant differences were detected for microbiological outcomes.