NIH Discovers New Thrombosis Target and Antibodies for Improved Detection and Therapy

National Cancer Institute (NCI) scientists identified soluble tissue factor (sTF) as a thrombosis driver and developed novel humanized monoclonal antibodies, such as 58B3 and 56E5, to target it. This innovation offers a safer therapeutic approach than existing anticoagulants, which carry significant bleeding risks, and provides a more sensitive method for early thrombosis detection.