JAMA Issues First U.S. Clinical Guidance on Vaping for Smoking Cessation

A Special Communication published in JAMA provides systematic recommendations for U.S. clinicians on using nicotine e-cigarettes for adult smoking cessation. The guidance suggests including e-cigarettes alongside FDA-approved cessation medications in risk-benefit discussions, citing high-certainty evidence that nicotine e-cigarettes achieve higher quit rates than nicotine replacement therapy. For adults choosing vaping to quit, the recommendations include using FDA-authorized products, ensuring sufficient nicotine delivery, and making a rapid, complete transition away from traditional cigarettes.