Positive Phase 2 Study Results for Alixorexton in Narcolepsy Type 1 Published in The Lancet Neurology

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Published: 2026-08-25
Category: health
Source: BioSpace (via The Lancet Neurology)

Alkermes plc announced the publication of data from the Vibrance-1 Phase 2 study of alixorexton in adults with narcolepsy type 1 (NT1) in The Lancet Neurology. The study demonstrated statistically significant and clinically meaningful improvements in wakefulness and cataplexy, as well as patient-reported outcomes related to disease severity, fatigue, cognition, and health-related quality of life. Alixorexton is an investigational, oral, selective orexin 2 receptor agonist.

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