Updated COVID-19 Vaccine Linked to Reduced Hospitalizations in Adults

A new study published in JAMA Internal Medicine indicates that the updated 2024-2025 COVID-19 vaccine was associated with a lower likelihood of medically attended COVID-19 outcomes in adults aged 18 and older, encompassing both immunocompetent and immunocompromised individuals. The CDC estimates that COVID-19 led to a significant number of hospitalizations and deaths in the United States between October 1, 2025, and September 12, 2026.