Experts Issue Updated Guidance for CAR T-Cell Therapy in Autoimmune Diseases

International experts have published revised best-practice recommendations for CAR T-cell therapy when used in severe autoimmune diseases, appearing in The Lancet Rheumatology. This 2026 guidance incorporates extensive clinical experience, aiming to establish scientific discipline and ensure patient safety as this advanced treatment expands from oncology into rheumatology clinics. The update is crucial for standardizing care and managing risks in this evolving therapeutic area.