Immune Protein CD37 Linked to Impaired Leg Muscle Healing in Peripheral Artery Disease

New research, published in the Journal of Translational Medicine, indicates that the immune protein CD37 hinders revascularization and muscle recovery in peripheral artery disease (PAD). This condition affects millions globally. The study suggests that blocking CD37 could potentially reprogram macrophages to promote healing, opening a new therapeutic avenue for critical limb-threatening ischemia.