Shorter Radiation Regimen Matches Longer Chemoradiation for Pancreatic Cancer Pre-Surgery

A randomized phase 2 clinical trial, known as the SOFT Preop trial, suggests that five sessions of stereotactic body radiation therapy (SBRT) before pancreatic cancer surgery can achieve similar tumor-related outcomes to weeks of chemoradiation, while significantly improving patients' physical function and reducing fatigue during treatment. The findings were presented at the American Society for Radiation Oncology (ASTRO) Annual Meeting.