Study Links Delayed Ovarian Cancer Surgery for BRCA1 Carriers to Higher Risk

A prospective cohort study in JAMA Surgery reveals that BRCA1 carriers delaying bilateral salpingo-oophorectomy until age 50 face a 23.9% ovarian cancer risk, significantly higher than the 4.2% risk at age 40. For BRCA2 carriers, the risk with the same delay is 3.5%. These findings emphasize the critical role of timely genetic testing and counseling for individuals considering risk-reducing surgery.