UK Regulator Strengthens Antidepressant Safety Warnings for Suicidal Thoughts and Sexual Dysfunction

The UK's MHRA is enhancing safety warnings for antidepressants, updating patient information leaflets with a new boxed warning about suicidal thoughts and behaviors. A new patient card will also reinforce key safety messages. Additionally, the term 'post-SSRI sexual dysfunction' (PSSD) will be explicitly added to highlight the risk of persistent sexual difficulties after treatment cessation, aiming to improve patient awareness.