Randomized Clinical Trial Shows Two-Drug HIV Therapy Effectively Penetrates Lymph Node Reservoirs

A randomized clinical trial has demonstrated that a two-drug antiretroviral regimen can effectively penetrate deep into lymph nodes, where HIV typically hides. Published in *Nature Communications*, the findings provide direct spatial evidence that this simplified therapy can exert antiviral pressure in these crucial anatomical sanctuaries, suggesting that treatment simplification may not compromise long-term viral persistence control.