Heart Drug Combination Significantly Reduces Kidney Damage in Septic Shock Surgery Patients

A study published in JAMA on October 28, 2026, found that a combination of dobutamine and norepinephrine significantly reduced the incidence of new or worsening kidney injuries in patients undergoing septic shock surgery. Fewer than a quarter of patients receiving the drug combination developed kidney injuries within a week after surgery, compared to approximately 35% in the standard care group.