AI-Powered Study Identifies Promising Small Molecule Inhibitors for Non-Small Cell Lung Cancer

A computational and artificial intelligence-based drug repurposing study has identified seven existing drugs as promising inhibitors of Ubiquitin Specific Protease 21 (USP21), a novel lung cancer protein target. USP21 inhibition has been shown to decrease levels of PD-L1, an immune checkpoint inhibitor, suggesting a new therapeutic strategy for non-small cell lung cancer.