Oklahoma Mandates Reporting of Alpha-Gal Syndrome to State Health Department

Oklahoma Senate Bill 1644, effective November 1, 2026, now mandates that Alpha-Gal Syndrome (AGS) be a reportable disease to the Oklahoma State Department of Health (OSDH). Clinical laboratories must report all positive AGS test results, including repeat positives for the same patient. This measure aims to improve surveillance of AGS, a potentially life-threatening allergy to a molecule found in most mammals, often triggered by tick bites.