CAR-T Cell Therapy Improves Mobility in Stiff Person Syndrome Patients

Preliminary study results published in JAMA Neurology indicate that a single infusion of modified CAR-T cells improved mobility and reduced muscle stiffness in 26 patients with stiff person syndrome. This finding offers promise for the rare neurological disease. However, further research is needed to address remaining questions about the therapy's long-term safety and duration of benefits.