3D Genome Mapping Identifies Crohn's Disease Genetic Risk Factors

A new study in *Nature Genetics*, co-led by Prof. Valeriya Malysheva, reveals how the 3D organization of DNA in rare immune cells contributes to genetic risk for Crohn's disease and other autoimmune conditions. The research highlights how DNA folding brings distant regulatory regions into contact with the genes they control, offering new insights into disease mechanisms.