Tumor Organoid Biobank Reveals Cancer Vulnerabilities for Therapy Development

Researchers from the Wellcome Sanger Institute and collaborators have established a comprehensive biobank of tumor organoids, published in Nature. This new open resource has enabled the creation of the first large-scale map of genes critical for cancer survival, identifying thousands of genetic dependencies. The findings offer promising avenues for developing more effective and less toxic cancer treatments by targeting both common and specific tumor vulnerabilities.