Scientists Discover Potential Weak Spot in Glioblastoma, Making Tumors More Vulnerable to Treatment

Researchers at The Ohio State University Comprehensive Cancer Center have identified a protein called SET as a potential target to weaken glioblastoma, one of the deadliest forms of brain cancer. Blocking SET prevented tumor formation in preclinical models, and targeting related proteins increased cancer cells' sensitivity to radiation by restoring the activity of the PP2A enzyme.