Scientists Uncover Major Brain Shifts Between Ages 50 and 75, Offering Clues to Neurodegenerative Diseases

Researchers have identified significant changes in how the human brain regulates and organizes its genome, particularly between the ages of 50 and 75. These findings reveal a decline in original immune cells, their replacement by more inflammatory cells, and a deterioration in the genome's 3D organization, providing new insights into why aging increases the risk of Alzheimer's and other neurodegenerative conditions.