Particle Engineering Advances to Improve Drug Formulation and Efficacy

Pharmaceutical scientists are preparing to showcase new translational research in drug formulation, with a special issue of the Journal of Pharmaceutical Investigation, scheduled for January 2027, focusing on advances in particle engineering and formulation science. The issue highlights how the physical form of a drug particle is crucial for its efficacy in patients, particularly for poorly soluble drug molecules, and explores techniques like micronization, nanonization, and amorphous solid dispersion to improve solubility, stability, and bioavailability.