Study in Nature Identifies Early Physiological Changes Preceding Menopause

A new study published in Nature, analyzing 300 million lab tests, indicates that physiological changes linked to perimenopause can commence over a decade before a woman's final menstrual period. The research identified significant shifts in endocrine, skeletal, hepatic, renal, and lipid systems at this point, which were absent in males and lessened by hormone therapy. This finding provides a quantifiable view of menopause and a strategy for understanding other life transitions.