Overactive Brain Immune Cells Linked to Alzheimer's Sleep Loss

Scientists at the University of Kentucky have identified overactive immune cells in the brain as an unexpected culprit behind sleep loss in Alzheimer's disease. Experiments with mice exhibiting Alzheimer's-like brain changes showed that temporarily removing these immune cells restored more than two hours of sleep per day without affecting amyloid plaques. This "paradigm-shifting" discovery suggests a promising new target for treating one of the most disruptive symptoms of Alzheimer's.