MIT Researchers Engineer Nanoparticles to Reprogram Immune Cells for Therapy

Scientists at MIT have created a new method using lipid nanoparticles to reprogram natural killer (NK) immune cells directly within the body. This innovation aims to simplify and reduce the cost of immune therapies, demonstrating potential in mouse models to eliminate tumors and reverse liver damage. The nanoparticles deliver messenger RNA, instructing NK cells to produce proteins that target diseased cells, offering a promising approach for cancer and autoimmune conditions. The findings were published in Nature Biotechnology.