DEA Temporarily Places O-Desmethyltramadol in Schedule I of Controlled Substances Act

The Drug Enforcement Administration (DEA) has issued a temporary order to place O-desmethyltramadol (O-DSMT) in Schedule I of the Controlled Substances Act, effective August 12, 2026. This action is based on a finding that scheduling O-DSMT is necessary to prevent an imminent hazard to public safety, imposing strict regulatory controls and sanctions on its handling.